Assistant Professor of Chemistry
at Williams since 2004
Goh, S. L.; Murthy, N.; Xu, M.; Frechet, J. M. J. "Crosslinked Microparticles as Carriers for the Delivery of Plasmid DNA for Vaccine Development" submitted.
Goh, S. L.; Dande, P.; Francis, M. B.; Frechet, J. M. J. "Solid-Phase Synthesis of Functionalized DNA-Dendron Conjugates as Building Blocks for Self-Assembled Dendrimers" in preparation.
Goh, S. L.; Murthy, N. Xu M..; Schuck, S. M.; Lau, L.; Dubber, M.; Frechet, J. M. J. "Encapsulation of Bioactive Molecules in Crosslinked Microgels" Polym. Mat. Sci. Eng. 2003, 88, 222-223; highlighted in Chem. Britain 2003, 39, 17.
Williams, S. C.; Goh, S. L.; Micheel, C. M.; Zanchet, D.; Parak W. J.; Alivisatos, A. P. "Producing Discrete and More Complex Nanoparticle Arrangements using Asymmetric Branched DNA Trimers" Abstr. Am. Chem. Soc., Div. Phys. Chem. 2003, 225, 56.
Frechet, J. M. J.; Murthy, N.; Dubber, M.; Goh, S.; Schuck, S.; Xu, M. "Synthetic macromolecules in therapeutics: Design, synthesis, and functional testing of polymers for protein and DNA transport and delivery" Abstr. Am. Chem. Soc., Div. Polym. Mat. Sci. Eng. 2003, 225, 39.
Goh, S. L.; Francis, M. B.; Frechet, J. M. J. "Self-assembled oligonucleotide-polyester dendrimers" Chem. Commun. 2002, 24, 2954-2955.
Micheel, C. M.; Jun, Y. W.; Williams, S. C.; Goh, S. L.; Zanchet, D.; Parak, W. J.; Gerion, D.; Pellegrino, T.; Alivisatos, A. P. "Novel characterization techniques for recent nanocrystal molecules" Abstr. Am. Chem. Soc., Div. Phys. Chem. 2002, 224, 248.
Francis, M. B.; Goh, S. L.; Dande, P.; De Jesus, O. L. P.; Frechet, J. M. J. "DNA-Dendrimer Conjugates for Drug Delivery" Polym. Mat. Sci. Eng. 2001, 84, 12-13.
Frechet, J. M. J.; Goh, S. L.; Franics, M. B. "Self-Assembly of Dendritic Light Harvesting Systems" Polym. Mat. Sci. Eng. 2001, 84, 710-711.
To investigate non-covalent assemblies based on biological system through:
Development of self-assembled hydrogels by integrating synthetic polymer and protein-mimetic components, resulting in materials with tunable properties and function.
Advancement of enzymatic poymerization methodologies for the preparation of functional polymers by exploring active site geometries through genetic engineering.
Evaluation of protein- and polysaccharide-based platforms for the targeted placement of active nono-catalyst centers in order to control macroscale function and architecure of these assemblies.