The natural world is built with many small components interacting in a simple but coordinated way. With a statistical view, we may make sense of the cooperative phenomena which emerge. For example, we can associate macroscopic thermodynamic properties with ensembles of microscopic states. With calculations and simple numerical exercises we shall probe a wide variety of physical phenomena: magnetism, gasses heat engines, thermal radiation, electrons in solids, polymers, random walks in fluids or in the stock market, and genomic information. Format: lecture, three hours per week/computer laboratory, 1 1/4 hours per week. Evaluation will be based on weekly problem sets, quizzes, labs and a final exam, all of which have a substantial quantitative component. Prerequisites: Physics 142, Physics 210. No enrollment limit (expected: 15).